H-Ras Recombinant Rabbit Monoclonal Antibody (23GB6035) | Invitrogen MA5-53940 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

H-Ras Recombinant Rabbit Monoclonal Antibody (23GB6035)

catalog :

MA5-53940

quantity :

100 uL

price :

US 539.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

23GB6035

reactivity :

human, mouse, rat

application :

western blot, flow cytometry

product information

Product Type :

Antibody

Product Name :

H-Ras Recombinant Rabbit Monoclonal Antibody (23GB6035)

Catalog # :

MA5-53940

Quantity :

100 uL

Price :

US 539.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 1:2,000, Western Blot: 1:1,000-1:5,000

Species :

Human, Mouse, Rat

Clone :

23GB6035

Isotype :

IgG

Storage :

-20 C

Description :

Monomeric G protein Ras functions as a molecular switch linking receptor and nonreceptor tyrosine kinase activation to a number of downstream signaling pathways leading to distinct cytoplasmic or nuclear events. Each mammalian cell contains three Ras proto-oncogene coding for closely related Ras proteins: H-, K-, N-Ras. Oncogenic mutations in Ras genes are present in ~30% of all human cancers. Constitutive activation of Ras due to mutations or overexpression stimulates proliferation and inhibition of apoptosis. K-Ras mutations are common in pancreatic, colorectal and nonsmall-cell lung carcinomas; H-Ras mutations are common in bladder, kidney and thyroid carcinomas; N-Ras mutations are found in melanoma, hematological malignancies and hepatocellular carcinaoma.

Immunogen :

A synthesized peptide derived from human GTPase HRAS (140-189AA).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:2,000, Western Blot: 1:1,000-1:5,000

Aliases :

C-BAS/HAS; c-Ha-ras; c-Ha-ras p21 protein; c-Ha-ras transgene; C-HA-RAS1; c-has/bas p21 protein; c-H-ras; c-rasHa; c-ras-Ki-2 activated oncogene; CTLO; GTP- and GDP-binding peptide B; GTPase HRas; GTPase HRas, N-terminally processed; GTPase Hras1; HAMSV; Ha-ras; Ha-Ras1 proto-oncoprotein; Harvey ras1 protein; Harvey rat sarcoma viral (v-Ha-ras) oncogene homolog; Harvey rat sarcoma viral oncogene homolog; Harvey rat sarcoma viral oncoprotein; Harvey rat sarcoma virus oncogene; Harvey rat sarcoma virus oncogene 1; Harvey-ras; Hras; H-ras; H-ras 1 protein; HRas proto-oncogene, GTPase; HRAS1; H-Ras-1; Hras-1; H-RASIDX; Kras2; p19 H-RasIDX protein; p21ras; ras; Ras family small GTP binding protein H-Ras; ras p21; RASH1; transformation gene: oncogene HAMSV; transforming protein P21; v-Ha-ras Harvey rat sarcoma viral oncogene homolog