Cdc23 Recombinant Rabbit Monoclonal Antibody (23GB3420) | Invitrogen MA5-53384 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cdc23 Recombinant Rabbit Monoclonal Antibody (23GB3420)

catalog :

MA5-53384

quantity :

100 uL

price :

US 539.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

23GB3420

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

Cdc23 Recombinant Rabbit Monoclonal Antibody (23GB3420)

Catalog # :

MA5-53384

Quantity :

100 uL

Price :

US 539.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:1,000, Western Blot: 1:1,000-1:5,000

Species :

Human, Mouse, Rat

Clone :

23GB3420

Isotype :

IgG

Storage :

-20 C

Description :

Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.

Immunogen :

A synthetic peptide of human Cdc23/APC8 (510-575AA).

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:1,000, Western Blot: 1:1,000-1:5,000

Aliases :

6030435O18; ANAPC8; anaphase promoting complex subunit 8; anaphase-promoting complex subunit 8; APC8; CDC23; CDC23 (cell division cycle 23, yeast, homolog); CDC23 cell division cycle 23; cell division cycle 23; cell division cycle 23 homolog; cell division cycle protein 23; cell division cycle protein 23 homolog; CUT23; cyclosome subunit 8; D18Ertd243e; zgc:56013