Complement C4 Recombinant Rabbit Monoclonal Antibody (23GB4985) | Invitrogen MA5-52894 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Complement C4 Recombinant Rabbit Monoclonal Antibody (23GB4985)

catalog :

MA5-52894

quantity :

100 uL

price :

US 429.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

23GB4985

reactivity :

mouse

application :

western blot, flow cytometry

product information

Product Type :

Antibody

Product Name :

Complement C4 Recombinant Rabbit Monoclonal Antibody (23GB4985)

Catalog # :

MA5-52894

Quantity :

100 uL

Price :

US 429.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Mouse

Applications :

Flow Cytometry: 1:2,000, Western Blot: 1:1,000-1:5,000

Species :

Mouse

Clone :

23GB4985

Isotype :

IgG

Storage :

-20 C

Description :

This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.

Immunogen :

A synthesized peptide derived from human C4 (1200-1280AA).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:2,000, Western Blot: 1:1,000-1:5,000

Aliases :

acidic C4; acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; C4; c4 complement; C4-1; C4a; C4a anaphylatoxin; C4A2; C4A3; C4A4; C4A6; C4AD; C4B; C4B_2; C4B1; C4B12; C4B2; C4B3; C4B5; C4b-A; C4b-B; C4BD; C4d-A; C4d-B; C4F; C4S; CH; Chido form of C4; CO4; Complement C4; Complement C4 alpha chain; Complement C4 beta chain; Complement C4 gamma chain; Complement C4-A; Complement C4-A alpha chain; Complement C4-B; Complement C4-B alpha chain; complement C4B1a; complement component 4 (within H-2S); complement component 4, gene 1; complement component 4A (Rodgers blood group); complement component 4B (Chido blood group); complement component 4B (Childo blood group); CPAMD2; CPAMD3; DADB-112B14.11; DAMC-258G8.6; FLJ60561; MGC164979; MHC class III region complement; RG; Rodgers form of C4; sex-limited protein; Slp; Ss