This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
DAPK1 Recombinant Rabbit Monoclonal Antibody (23GB3565)
catalog :
MA5-52617
quantity :
20 uL
price :
US 179.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
23GB3565
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, flow cytometry
product information
Product Type :
Antibody
Product Name :
DAPK1 Recombinant Rabbit Monoclonal Antibody (23GB3565)
Catalog # :
MA5-52617
Quantity :
20 uL
Price :
US 179.00
Clonality :
Recombinant Monoclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Flow Cytometry: 1:2,000, Immunocytochemistry: 1:1,000, Western Blot: 1:1,000-1:5,000
Species :
Human, Mouse, Rat
Clone :
23GB3565
Isotype :
IgG
Storage :
-20 C
Description :
DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor. DAPK1 is involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and authophagy. It regulates both type I apoptotic and type II autophagic cell death signal, depending on the cellular setting. Type I apoptotic cell death is caspase-dependent, type II authophagic cell death is caspase-independent. DAPK1 phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. It also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.
Immunogen :
A synthetic peptide of human DAP Kinase 1 (300-350AA).
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:2,000, Immunocytochemistry: 1:1,000, Western Blot: 1:1,000-1:5,000
Aliases :
D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA