CD73 Recombinant Rat Monoclonal Antibody (YDBYT 208.3) | Invitrogen MA5-51884 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD73 Recombinant Rat Monoclonal Antibody (YDBYT 208.3)

catalog :

MA5-51884

quantity :

200 ug

price :

US 529.00

clonality :

recombinant

host :

rat

conjugate :

nonconjugated

clone name :

YDBYT 208.3

reactivity :

mouse

application :

immunocytochemistry

product information

Product Type :

Antibody

Product Name :

CD73 Recombinant Rat Monoclonal Antibody (YDBYT 208.3)

Catalog # :

MA5-51884

Quantity :

200 ug

Price :

US 529.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rat

Reactivity :

Mouse

Applications :

Immunocytochemistry: Assay-dependent

Species :

Mouse

Clone :

YDBYT 208.3

Isotype :

IgG2b, kappa

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CD73 (Ecto-5-prime-nucleotidase, 5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. CD73 consists of a dimer of 2 identical 70 kDa subunits bound externally to the plasma membrane by a glycosyl phosphatidyl inositol linkage. CD73 is used as a marker of lymphocyte differentiation. Consequently, a deficiency of CD73 occurs in a variety of immunodeficiency diseases. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from CD73 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. The CD73 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations. Defects in the CD73 gene can lead to the calcification of joints and arteries, and intestinal tuberculosis. Two transcript variants encoding different isoforms of CD73 have been found.

Immunogen :

Murine CD73.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-dependent

Aliases :

2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; NTE; Purine 5-Prime-Nucleotidase