IL-10 Recombinant Rat Monoclonal Antibody (9D7) | Invitrogen MA5-51866 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-10 Recombinant Rat Monoclonal Antibody (9D7)

catalog :

MA5-51866

quantity :

200 ug

price :

US 529.00

clonality :

recombinant

host :

rat

conjugate :

nonconjugated

clone name :

9D7

The same clone is also sold as:

MABTECH: 3430-3-1000, 3430-3-250, 3430-3N-500

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

IL-10 Recombinant Rat Monoclonal Antibody (9D7)

Catalog # :

MA5-51866

Quantity :

200 ug

Price :

US 529.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rat

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, In vitro Assay: Assay-dependent, Neutralization: Assay-dependent

Species :

Human

Clone :

9D7

Isotype :

IgG1, kappa

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.

Immunogen :

Rats are immunised with synthetic oligopeptide (containing an N-terminal cysteine)-carrier protein conjugates.

Format :

Liquid

Applications w/Dilutions :

Aliases :

CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF