Phospho-FOXO1/FOXO3/FOXO4 (Thr24, Thr32, Thr28) Recombinant Rabbit Monoclonal Antibody (3V0U2)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-FOXO1/FOXO3/FOXO4 (Thr24, Thr32, Thr28) Recombinant Rabbit Monoclonal Antibody (3V0U2)

catalog :

MA5-51552

quantity :

100 uL

price :

US 424.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

3V0U2

reactivity :

human, mouse

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

Phospho-FOXO1/FOXO3/FOXO4 (Thr24, Thr32, Thr28) Recombinant Rabbit Monoclonal Antibody (3V0U2)

Catalog # :

MA5-51552

Quantity :

100 uL

Price :

US 424.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

ELISA: 1 ug/mL, Western Blot: 1:1,000-1:5,000

Species :

Human, Mouse

Clone :

3V0U2

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

FOXO1 + FOX3 + FOX4 belong to the forkhead family of transcription factors. FOXO1 (FKHR or ForkHead in Rhabdomyosarcoma) is a 70 kDa protein. Recent studies have shown that this protein can act as either a coactivator or a corepressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the C terminus of the FOXO1A protein. The specific function of the gene has not yet been determined.FOX3 probably functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of the FOXO3 gene with the MLL gene is associated with secondary acute leukemia.FOX4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.

Immunogen :

A synthetic phosphorylated peptide around T24 & T32 & T28 of human FOXO1/FOXO3A/FOXO4FOXO1.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Western Blot: 1:1,000-1:5,000

Aliases :

1110048B16Rik; 2010203A17Rik; AF6q21; AF6q21 protein; AFX; AFX1; Afxh; AI876417; C76856; FKH1; FKHR; Fkhr1; Fkhr2; Fkhr3; FKHRL1; FKHRL1P2; fork head domain transcription factor AFX1; forkhead box O1; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box O3; forkhead box O3A; forkhead box O4; forkhead box protein O1; Forkhead box protein O1A; forkhead box protein O3; Forkhead box protein O4; forkhead homolog (rhabdomyosarcoma) like 1; forkhead in rhabdomyosarcoma; Forkhead in rhabdomyosarcoma-like 1; forkhead protein; forkhead protein 1; forkhead protein FKHR2; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1; Foxo1; FOXO1A; FOXO2; FOXO3; Foxo3a; FOXO4; MGC120490; Mllt7; myeloid/lymphoid or mixed lineage-leukemia translocation to 7 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7; RGD1561201