This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Caspase 1 p20 Recombinant Rabbit Monoclonal Antibody (1N2U7)
catalog :
MA5-51502
quantity :
100 uL
price :
US 424.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
1N2U7
reactivity :
human
application :
western blot, ELISA
product information
Product Type :
Antibody
Product Name :
Caspase 1 p20 Recombinant Rabbit Monoclonal Antibody (1N2U7)
Catalog # :
MA5-51502
Quantity :
100 uL
Price :
US 424.00
Clonality :
Recombinant Monoclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
ELISA: 1 ug/mL, Western Blot: 1:2,000-1:8,000
Species :
Human
Clone :
1N2U7
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Caspase-1 (CASP1) is a thiol protease that cleaves IL-1 beta between Asp and Ala. This cleavage causes the release of the mature cytokine which is involved in a variety of inflammatory processes. CASP1 is important for defense against pathogen. It cleaves and activates sterol regulatory element binding proteins (SREBPs). CASP1 also promotes apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, CASP1 controls antiviral immunity through the cleavage of CGAS and renders it inactive.
Immunogen :
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Caspase-1 p20(NP_001244047.1).
Format :
Liquid
Applications w/Dilutions :
ELISA: 1 ug/mL, Western Blot: 1:2,000-1:8,000
Aliases :
CASP1; CASP-1; CASP1 nirs variant 1; caspase 1; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase); caspase-1; Caspase-1 subunit p10; Caspase-1 subunit p20; Ice; IL-1 beta-converting enzyme; IL-1B converting enzyme; IL1BC; IL-1BC; IL1BCE; IL1B-convertase; interleukin 1 beta-converting enzyme; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; Interleukin 1beta converting enzyme; interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; p45
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA