This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
LRP6 Recombinant Rabbit Monoclonal Antibody (6Y9J1)
catalog :
MA5-51445
quantity :
100 uL
price :
US 424.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
6Y9J1
reactivity :
human, mouse, rat
application :
western blot, ELISA
product information
Product Type :
Antibody
Product Name :
LRP6 Recombinant Rabbit Monoclonal Antibody (6Y9J1)
Catalog # :
MA5-51445
Quantity :
100 uL
Price :
US 424.00
Clonality :
Recombinant Monoclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
ELISA: 1 ug/mL, Western Blot: 1:1,000-1:5,000
Species :
Human, Mouse, Rat
Clone :
6Y9J1
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.
Immunogen :
A synthetic peptide corresponding to a sequence within amino acids 900-1000 of human LRP6 (NP_002327.2).
Format :
Liquid
Applications w/Dilutions :
ELISA: 1 ug/mL, Western Blot: 1:1,000-1:5,000
Aliases :
ADCAD2; C030016K15Rik; Cd; crooked; FLJ90062; FLJ90421; Gw; LDL receptor related protein 6; low density lipoprotein receptor-related protein 6; low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6; low density lipoprotein-related protein 6; low-density lipoprotein receptor-related protein 6; lpr6; LRP6; LRP-6; ska ; ska26; skax26; STHAG7
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA