SETD6 Recombinant Rabbit Monoclonal Antibody (1Q1Z3) | Invitrogen MA5-51377 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SETD6 Recombinant Rabbit Monoclonal Antibody (1Q1Z3)

catalog :

MA5-51377

quantity :

100 uL

price :

US 424.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

1Q1Z3

reactivity :

human, mouse, rat

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

SETD6 Recombinant Rabbit Monoclonal Antibody (1Q1Z3)

Catalog # :

MA5-51377

Quantity :

100 uL

Price :

US 424.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 1 ug/mL, Western Blot: 1:1,000-1:5,000

Species :

Human, Mouse, Rat

Clone :

1Q1Z3

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

SETD6 (SET domain-containing protein 6) is a 473 amino acid protein that belongs to the SETD6 family. Containing one SET domain, SETD6 is structurally similar to the Rubisco large subunit methyltransferase. SETD6 is a proteinlysine N-methyltransferase that specifically monomethylates 'Lys-310' of the NF B p65 subunit of NF B complex, leading to down-regulate NF B transcription factor activity. SETD6-mediated methylation renders NF B p65 inert and attenuates NF B p65-driven transcriptional programs, including inflammatory responses in primary immune cells. The SETD6-initiated lysine-methylation signaling cascade acts to restrain activation of NF B-mediated inflammatory responses in diverse cell types.

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 310-473 of human SETD6 (NP_001153777.1).

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Western Blot: 1:1,000-1:5,000

Aliases :

0610039J04Rik; 3110004G14Rik; AI413388; C76402; N-lysine methyltransferase SETD6; RGD1560538; SET domain containing 6; SET domain-containing protein 6; SETD6