This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IL-10 Recombinant Rabbit Monoclonal Antibody (1P10I3)
catalog :
MA5-51269
quantity :
100 uL
price :
US 424.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
1P10I3
reactivity :
mouse
application :
western blot
product information
Product Type :
Antibody
Product Name :
IL-10 Recombinant Rabbit Monoclonal Antibody (1P10I3)
Catalog # :
MA5-51269
Quantity :
100 uL
Price :
US 424.00
Clonality :
Recombinant Monoclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Mouse
Applications :
Western Blot: 1:1,000-1:5,000
Species :
Mouse
Clone :
1P10I3
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
Immunogen :
Recombinant fusion protein containing a sequence corresponding to amino acids 19-178 of rat IL10 (NP_036986.2).
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1:1,000-1:5,000
Aliases :
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA