CYP3A4 Recombinant Rabbit Monoclonal Antibody (7K5L10) | Invitrogen MA5-51247 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CYP3A4 Recombinant Rabbit Monoclonal Antibody (7K5L10)

catalog :

MA5-51247

quantity :

100 uL

price :

US 424.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

7K5L10

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

CYP3A4 Recombinant Rabbit Monoclonal Antibody (7K5L10)

Catalog # :

MA5-51247

Quantity :

100 uL

Price :

US 424.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: 1 ug/mL, Immunocytochemistry: 1:100-1:800, Western Blot: 1:2,000-1:12,000

Species :

Human

Clone :

7K5L10

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.

Immunogen :

A synthetic peptide corresponding to a sequence within amino acids 400-503 of human CYP3A4 (NP_059488.2).

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Immunocytochemistry: 1:100-1:800, Western Blot: 1:2,000-1:12,000

Aliases :

1,8-cineole 2-exo-monooxygenase; albendazole monooxygenase; Albendazole monooxygenase (sulfoxide-forming); Albendazole sulfoxidase; cholesterol 25-hydroxylase; CP33; CP34; CYP; CYP3A; CYP3A3; CYP3A4; CYPIIIA3; CYPIIIA4; Cytochrome P450 3A3; cytochrome P450 3A4; cytochrome P450 family 3 subfamily A member 4; cytochrome P450 HLp; Cytochrome P450 NF-25; cytochrome P450, family 3, subfamily A, polypeptide 4; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4; cytochrome P450-PCN1; glucocorticoid-inducible P450; HLP; MGC126680; NF-25; Nifedipine oxidase; P450; P450C3; P450-III, steroid inducible; P450PCN1; P450-PCN1; Quinine 3-monooxygenase; taurochenodeoxycholate 6-alpha-hydroxylase