This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CRHBP Monoclonal Antibody (D2)
catalog :
MA5-50972
quantity :
20 uL
price :
US 181.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D2
reactivity :
rat
application :
western blot
product information
Product Type :
Antibody
Product Name :
CRHBP Monoclonal Antibody (D2)
Catalog # :
MA5-50972
Quantity :
20 uL
Price :
US 181.00
Clonality :
Monoclonal
Purity :
Protein A/G
Host :
Mouse
Reactivity :
Rat
Applications :
Western Blot: 0.1-2 ug/mL
Species :
Rat
Clone :
D2
Isotype :
IgG1, kappa
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Response to stress in mammals requires an intact hypothalamic-pituitary-adrenal axis. The proximal part of the response is mediated by secretion of corticotropin-releasing hormone (CRH) by the paraventricular nucleus of the hypothalamus. CRH is a 41 amino acid peptide derived by enzymatic cleavage from a 191 amino acid preprohormone. CRH is produced not only in the hypothalamus but also in peripheral tissues, such as T lymphocytes; it is highly expressed in human placenta. Glucocorticoids stimulate placental CRH synthesis and secretion in primary cultures of human placenta. This stimulation is in contrast to the glucocorticoid suppression of CRH expression in hypothalamus. The gene which encodes CRH maps to human chromosome 8q13. Human plasma contains a CRH-binding protein, CRH-BP (also designated CRF-BP) which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. The gene which encodes CRF-BP maps to human chromosome 5q11.2-q13.3.
Immunogen :
Recombinant Rat CRHBP protein, Tyr25-Leu322 (Accession #P24388)
Format :
Liquid
Applications w/Dilutions :
Western Blot: 0.1-2 ug/mL
Aliases :
corticotropin releasing factor binding protein; corticotropin releasing hormone binding protein; corticotropin releasing hormone-binding protein; corticotropin-releasing factor-binding protein; Corticotropin-releasing hormone-binding protein; CRF-binding protein; CRFBP; CRF-BP; Crhbp; CRH-BP
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA