GABBR1 Recombinant Rabbit Monoclonal Antibody (JE60-09) | Invitrogen MA5-50825 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GABBR1 Recombinant Rabbit Monoclonal Antibody (JE60-09)

catalog :

MA5-50825

quantity :

100 uL

price :

US 470.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

JE60-09

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

GABBR1 Recombinant Rabbit Monoclonal Antibody (JE60-09)

Catalog # :

MA5-50825

Quantity :

100 uL

Price :

US 470.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunohistochemistry (Paraffin): 1:1,000, Western Blot: 1:1,000

Species :

Human, Mouse

Clone :

JE60-09

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Receptor for GABA. The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.

Immunogen :

Recombinant protein within Human GABA B Receptor 1 aa 35-134/961.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:1,000, Western Blot: 1:1,000

Aliases :

bM573K1.1; bM573K1.1.1 (gamma-aminobutyric acid (GABA) B receptor, 1a); DAAP-188P13.3; dJ271M21.1.1; dJ271M21.1.2; FLJ92613; GABA(B) receptor; GABAB; GABA-B receptor 1; GABA-B receptor, R1 subunit; GABAB1; Gaba-b1; GABAbR1; GABA-BR1; GABA-B-R1; Gababr1 receptor; Gaba-b-r1a; Gaba-br1a receptor; GABA-BR1b receptor; Gabbr1; GABBR1-3; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) B receptor 1; gamma-aminobutyric acid (GABA) B receptor, 1; gamma-aminobutyric acid (GABA-B) receptor, 1; gamma-aminobutyric acid type B receptor subunit 1; GB1; GBR1; GPRC3A; HGB1a; OTTHUMP00000109099; OTTHUMP00000214725; seven transmembrane helix receptor