AOX1 Recombinant Rabbit Monoclonal Antibody (PSH0-17) | Invitrogen MA5-50783 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

AOX1 Recombinant Rabbit Monoclonal Antibody (PSH0-17)

catalog :

MA5-50783

quantity :

100 uL

price :

US 470.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

PSH0-17

The same clone is also sold as:

Novus Biologicals: NBP3-32018

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

AOX1 Recombinant Rabbit Monoclonal Antibody (PSH0-17)

Catalog # :

MA5-50783

Quantity :

100 uL

Price :

US 470.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 1:500-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500

Species :

Human, Mouse, Rat

Clone :

PSH0-17

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

AOX1 (Aldehyde oxidase 1) is a 1338 amino acid cytoplasmic protein that catalyzes the oxidation of a variety of aldehydes, leading to the production of hydrogen peroxide. Under certain conditions, AOX1 can catalyze the formation of the superoxide free radical. Defects in oxygen radical metabolism have been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS), an autosomal dominant neurodegenerative disorder characterized by the death of motor neurons in the spinal cord, brain and brainstem. Significantly, AOX1 is highly expressed in the ventral horn of the spinal cord and the gene that encodes AOX1 is located in a chromosomal region that is frequently found to be implicated in ALS2. This evidence suggests that AOX1 is a candidate gene for ALS2.

Immunogen :

Synthetic peptide within human AOX1 aa 1301-1338/1338.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:500-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500

Aliases :

AI196512; AI255253; Aldehyde oxidase; aldehyde oxidase (female form); aldehyde oxidase 1; aldehyde oxidase 2; Ao; AOH1; Aox1; Aox-1; Aox2; Aox-2; Azaheterocycle hydroxylase; azaheterocycle hydroxylase 1; Moro; Retinal oxidase; Ro