Transferrin Receptor Recombinant Human Monoclonal Antibody (7H12)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Transferrin Receptor Recombinant Human Monoclonal Antibody (7H12)

catalog :

MA5-50098

quantity :

100 uL

price :

US 414.00

clonality :

recombinant

host :

human

conjugate :

nonconjugated

clone name :

7H12

reactivity :

human

product information

Product Type :

Antibody

Product Name :

Transferrin Receptor Recombinant Human Monoclonal Antibody (7H12)

Catalog # :

MA5-50098

Quantity :

100 uL

Price :

US 414.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity chromatography

Host :

Human

Reactivity :

Human

Applications :

ELISA: Assay-dependent

Species :

Human

Clone :

7H12

Isotype :

IgG1

Storage :

-20 C or -80 C if preferred

Description :

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

Immunogen :

Recombinant Human TFRC protein

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent

Aliases :

2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr