Desmoglein 3 Recombinant Mouse Monoclonal Antibody (4C2) | Invitrogen MA5-49981 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Desmoglein 3 Recombinant Mouse Monoclonal Antibody (4C2)

catalog :

MA5-49981

quantity :

100 uL

price :

US 414.00

clonality :

recombinant

host :

mouse

conjugate :

nonconjugated

clone name :

4C2

reactivity :

human, mouse

product information

Product Type :

Antibody

Product Name :

Desmoglein 3 Recombinant Mouse Monoclonal Antibody (4C2)

Catalog # :

MA5-49981

Quantity :

100 uL

Price :

US 414.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ELISA: Assay-dependent

Species :

Human, Mouse

Clone :

4C2

Isotype :

IgG1

Storage :

-20 C or -80 C if preferred

Description :

Desmoglein 3 (Dsg3), also known as Cadherin family member 6 (CDHF6), is a member of the desmosomal cadherin family and plays a critical role in cell-cell adhesion. It is predominately expressed in stratified squamous epithelium, including the skin, oral mucosa, and esophagus. Desmoglein 3 has been characterized as the auto-antigen of pemphigus vulgaris (PV), a life-threatening autoimmune disease. Binding of anti-Desmoglein 3 autoantibodies causes the loss of cell-cell adhesion, which clinically manifests as blisters on the skin and oral mucosa, and histologically as suprabasilar acantholysis.

Immunogen :

Recombinant Human DSG3 protein

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent

Aliases :

130 kDa pemphigus vulgaris antigen; 130 kDa pemphigus vulgaris antigen homolog; bal; balding; Cadherin family member 6; CDHF6; desmoglein 3; desmoglein-3; DKFZp686P23184; Dsg3; PVA