TLR7 Recombinant Rabbit Monoclonal Antibody (6E5) | Invitrogen MA5-49844 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TLR7 Recombinant Rabbit Monoclonal Antibody (6E5)

catalog :

MA5-49844

quantity :

100 uL

price :

US 414.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

6.00E+05

reactivity :

human

application :

immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

TLR7 Recombinant Rabbit Monoclonal Antibody (6E5)

Catalog # :

MA5-49844

Quantity :

100 uL

Price :

US 414.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Immunohistochemistry (Paraffin): 1:50-1:200

Species :

Human

Clone :

6.00E+05

Isotype :

IgG

Storage :

-20 C or -80 C if preferred

Description :

TLR7 is a 10 amino acid long highly conserved membrane protein belonging to the Toll-like receptor (TLR) family with 27 LRR (leucine-rich) repeats and a TIR domain. TLR7 plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 is activated by infections with single-stranded RNA viruses, including influenza virus and vesicular stomatitis virus (VSV). TLR7 is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8. TLR7 also acts via MyD88 and TRAF6, leading to NF-kappaB activation, cytokine secretion and the inflammatory response. TLR7 recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.

Immunogen :

A synthesized peptide derived from human TLR7

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunohistochemistry (Paraffin): 1:50-1:200

Aliases :

RGD1563357; RP23-139P21.3; Tlr7; TLR7-like; toll like receptor 7; toll-like receptor 7; toll-like receptor 7-like; UNQ248/PRO285