This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PD-1 Recombinant Llama Monoclonal Antibody (F4-2D7)
catalog :
MA5-49328
quantity :
100 ug
price :
US 434.00
clonality :
recombinant
host :
llama
conjugate :
nonconjugated
clone name :
F4-2D7
reactivity :
human
application :
flow cytometry
product information
Product Type :
Antibody
Product Name :
PD-1 Recombinant Llama Monoclonal Antibody (F4-2D7)
Catalog # :
MA5-49328
Quantity :
100 ug
Price :
US 434.00
Clonality :
Recombinant Monoclonal
Purity :
Affinity chromatography
Host :
Llama
Reactivity :
Human
Applications :
ELISA: 10 ug/mL, Flow Cytometry: 10 ug/mL
Species :
Human
Clone :
F4-2D7
Isotype :
scFv
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of 'danger signals' such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.
Immunogen :
A recombinant protein corresponding to amino acids 25-167 of human PD-1.
Format :
Liquid
Applications w/Dilutions :
ELISA: 10 ug/mL, Flow Cytometry: 10 ug/mL
Aliases :
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA