This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Optineurin Monoclonal Antibody (3D8)
catalog :
MA5-49177
quantity :
100 ug
price :
US 404.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3D8
reactivity :
human, mouse, rat
application :
western blot, flow cytometry
product information
Product Type :
Antibody
Product Name :
Optineurin Monoclonal Antibody (3D8)
Catalog # :
MA5-49177
Quantity :
100 ug
Price :
US 404.00
Clonality :
Monoclonal
Purity :
Antigen affinity chromatography
Host :
Mouse
Reactivity :
Human, Mouse, Rat
Applications :
Flow Cytometry: Assay-dependent, Western Blot: 0.1-0.5 ug/mL
Species :
Human, Mouse, Rat
Clone :
3D8
Isotype :
IgG2b
Storage :
-20 C
Description :
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14. 7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
Immunogen :
E.coli-derived human Optineurin recombinant protein (Position: R241-I577).
Format :
Lyophilized
Applications w/Dilutions :
Flow Cytometry: Assay-dependent, Western Blot: 0.1-0.5 ug/mL
Aliases :
14.7K-interacting protein 2; 4930441O07Rik; Ag9 C5; ALS12; E3-14.7K-interacting protein; FIP 2; FIP2; FIP-2; FIP-2-like protein; GLC1E; HIP 7; HIP7; HIP-7; Huntingtin interacting protein L; huntingtin yeast partner L; Huntingtin-interacting protein 7; huntingtin-interacting protein L; HYPL; NEMO-related protein; NRP; Optic neuropathy-inducing protein; optineurin; Optn; TFIIIA IntP; TFIIIA-IntP; transcription factor IIIA-interacting protein; transcrption factor IIIA-interacting protein; tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains; Uban
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA