NOD1 Monoclonal Antibody (2A10) | Invitrogen MA5-49081 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NOD1 Monoclonal Antibody (2A10)

catalog :

MA5-49081

quantity :

100 ug

price :

US 572.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

2A10

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section

product information

Product Type :

Antibody

Product Name :

NOD1 Monoclonal Antibody (2A10)

Catalog # :

MA5-49081

Quantity :

100 ug

Price :

US 572.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Rat

Reactivity :

Human

Applications :

Immunocytochemistry: 1:50, Immunohistochemistry (Frozen): 1:50, Immunoprecipitation: 1:50, Western Blot: 1:50

Species :

Human

Clone :

2A10

Isotype :

IgG2a

Storage :

4 C

Description :

NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD1 contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and ten tandem leucine-rich repeats (LRRs) in its C-terminus. The CARD is involved in apoptotic signaling, and NOD1 activates caspase-9 and NF-kappa-B. LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.

Immunogen :

GST-tagged CARD domain (aa1-126) of Nod1 expressed in bacteria

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50, Immunohistochemistry (Frozen): 1:50, Immunoprecipitation: 1:50, Western Blot: 1:50

Aliases :

C230079P11; Card4; caspase recruitment domain 4; caspase recruitment domain family, member 4; caspase recruitment domain-containing protein 4; CLR7.1; F830007N14Rik; NLR family, CARD domain containing 1; Nlrc1; Nod1; nucleotide binding oligomerization domain containing 1; nucleotide-binding oligomerization domain containing 1; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1; nucleotide-binding oligomerization domain-containing protein 1; RGD1562269