This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CHRM2 Monoclonal Antibody (B8E5)
catalog :
MA5-49029
quantity :
100 ug
price :
US 626.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B8E5

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
product information
Product Type :
Antibody
Product Name :
CHRM2 Monoclonal Antibody (B8E5)
Catalog # :
MA5-49029
Quantity :
100 ug
Price :
US 626.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human
Applications :
Functional Assay: 1:50, Immunocytochemistry: 1:50, Immunohistochemistry (Frozen): 1:50, Inhibition Assays: 1:50, Western Blot: 1:50
Species :
Human
Clone :
B8E5
Isotype :
IgG2a
Storage :
4 C
Description :
Muscarinic cholinergic receptor 2 (CHRM2) is an Acetylcholine Receptor has been suggested to function as a presynaptic autoreceptor that inhibits acetylcholine release. The M2 receptor has also been suggested to mediate smooth muscle contractility. Alzheimer's disease (AD) involves selective loss of M2 subtype receptors in cortical and hippocampal regions of the human brain. Increase in M2 receptor heterozygosity has been associated with depression in women. The M2 receptor has been reported to be expressed in various regions of the brain including the cerebellum, cerebral cortex, hippocampus, medulla, striatum, and thalamus, and in lung and prostate.
Immunogen :
Peptide VRTVEDGECYIQFFSNAAVTFGTAI(C): Human second extracellular loop residues 168-192
Format :
Liquid
Applications w/Dilutions :
Functional Assay: 1:50, Immunocytochemistry: 1:50, Immunohistochemistry (Frozen): 1:50, Inhibition Assays: 1:50, Western Blot: 1:50
Aliases :
7TM receptor; acetylcholine receptor; acetylcholine receptor, muscarinic 2; AChR M2; AChR-M2; Acm2; cardiac muscarinic acetylcholine receptor; cholinergic receptor; cholinergic receptor muscarinic 2; cholinergic receptor, muscarinic 2; cholinergic receptor, muscarinic 2, cardiac; cholinergic receptor, muscarinic 2, isoform a; Chrm2; Chrm-2; FLJ43243; HM2; M2; M2 muscarinic acetylcholine receptor; m2AChR; M2-mAChR; MGC120006; MGC120007; muscarinic acetylcholine receptor 2; muscarinic acetylcholine receptor m2; muscarinic M2 receptor; muscarinic receptor m2; unnamed protein product
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA