mGluR5 Monoclonal Antibody (8H5D5) | Invitrogen MA5-48482 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

mGluR5 Monoclonal Antibody (8H5D5)

catalog :

MA5-48482

quantity :

100 ug

price :

US 484.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8H5D5

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Product Type :

Antibody

Product Name :

mGluR5 Monoclonal Antibody (8H5D5)

Catalog # :

MA5-48482

Quantity :

100 ug

Price :

US 484.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: 1:250-1:1,000

Species :

Human

Clone :

8H5D5

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.

Immunogen :

Purified recombinant fragment of human GRM5 (AA: extra 458-580) expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: 1:250-1:1,000

Aliases :

6430542K11Rik; A830007B11Rik; AI850523; D16Ium24; D16Ium24e; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member E; Glu5R; Glur5; Glur-5; Glurbeta1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 5; GPRC1A; GPRC1E; GRM 1; GRM 5; GRM1; GRM1 alpha; GRM1A; Grm5; metabotropic 1; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGC25101; mGlu1; mGlu5; mGluR; mGluR1; mGluR1 alpha; mGluR1A; MGLUR5; mGluR5a; mGluR5b; PPP1R86; protein phosphatase 1, regulatory subunit 86