CD16b Monoclonal Antibody (8F1C10) | Invitrogen MA5-48455 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD16b Monoclonal Antibody (8F1C10)

catalog :

MA5-48455

quantity :

100 ug

price :

US 484.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8F1C10

reactivity :

human

application :

western blot, ELISA, flow cytometry

product information

Product Type :

Antibody

Product Name :

CD16b Monoclonal Antibody (8F1C10)

Catalog # :

MA5-48455

Quantity :

100 ug

Price :

US 484.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Western Blot: 1:500-1:2,000

Species :

Human

Clone :

8F1C10

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FCGR3A is associated, with FcepsilonRI-beta subunit. Besides IgG, FCGR3A can be triggered also by oligomeric IgE. FCGR3B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a pro-adhesive phenotype. Diseases associated with CD16 dysfunction include immunodeficiency 20 and systemic lupus erythematosus.

Immunogen :

Purified recombinant fragment of human CD16B (AA: 17-200) expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Western Blot: 1:500-1:2,000

Aliases :

CD16; CD16B; Fc fragment of IgG receptor IIIb; Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor IIIb; FCG3; Fc-gamma receptor IIIb (CD 16); Fc-gamma RIII; fc-gamma RIIIb; Fc-gamma RIII-beta; FCGR3; FCGR3B; FcR-10; FCRIII; FCRIIIb; IGFR3; IgG Fc receptor III-1; low affinity immunoglobulin gamma Fc region receptor III-B