H4ac pan-acetyl (K8,K12,K16) Chimeric Recombinant Rabbit Monoclonal Antibody (KM-2)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

H4ac pan-acetyl (K8,K12,K16) Chimeric Recombinant Rabbit Monoclonal Antibody (KM-2)

catalog :

MA5-48313

quantity :

200 ug

price :

US 520.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

KM-2

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Product Type :

Antibody

Product Name :

H4ac pan-acetyl (K8,K12,K16) Chimeric Recombinant Rabbit Monoclonal Antibody (KM-2)

Catalog # :

MA5-48313

Quantity :

200 ug

Price :

US 520.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Flow Cytometry: 1:100, Immunocytochemistry: 10 ug/mL, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Clone :

KM-2

Isotype :

IgG, kappa

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

H4 acetylation at lysine residues 8, 12, and 16 is a well-characterized post-translational modification that is associated with transcriptional activation. This modification is catalyzed by histone acetyltransferases (HATs) and is often found at promoter regions of actively transcribed genes. It is believed to facilitate chromatin remodeling and transcription factor recruitment, ultimately leading to increased gene expression. However, the precise mechanisms by which H4 acetylation at these specific lysine residues contributes to gene regulation are still under investigation.

Immunogen :

KM-2 antibody was derived from an MRL/lpr lupus mouse.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Flow Cytometry: 1:100, Immunocytochemistry: 10 ug/mL, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent