IL-6 Receptor (CD126) Chimeric Recombinant Rabbit Monoclonal Antibody (D7715A7)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-6 Receptor (CD126) Chimeric Recombinant Rabbit Monoclonal Antibody (D7715A7)

catalog :

MA5-48200

quantity :

200 ug

price :

US 520.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

D7715A7

The same clone is also sold as:

BioLegend: 115815, 115813, 115811, 115803, 115812, 115814, 115816, 115806, 115805

reactivity :

mouse

application :

immunocytochemistry, flow cytometry

product information

Product Type :

Antibody

Product Name :

IL-6 Receptor (CD126) Chimeric Recombinant Rabbit Monoclonal Antibody (D7715A7)

Catalog # :

MA5-48200

Quantity :

200 ug

Price :

US 520.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Mouse

Applications :

Flow Cytometry: 1:100, Functional Assay: Assay-dependent, Immunocytochemistry: 10 ug/mL, Inhibition Assays: Assay-dependent

Species :

Mouse

Clone :

D7715A7

Isotype :

IgG, kappa

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

Immunogen :

This antibody was raised by immunising Lewis rats with OKT4 cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:100, Functional Assay: Assay-dependent, Immunocytochemistry: 10 ug/mL, Inhibition Assays: Assay-dependent

Aliases :

CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991