CD137 Chimeric Recombinant Rat Monoclonal Antibody (LOB12.3) | Invitrogen MA5-48148 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD137 Chimeric Recombinant Rat Monoclonal Antibody (LOB12.3)

catalog :

MA5-48148

quantity :

200 ug

price :

US 520.00

clonality :

recombinant

host :

rat

conjugate :

nonconjugated

clone name :

LOB12.3

The same clone is also sold as:

Bio X Cell: BE0169-5MG, BE0169-25MG, BE0169-50MG, BE0169-100MG, BE0169-1MG

reactivity :

mouse

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

CD137 Chimeric Recombinant Rat Monoclonal Antibody (LOB12.3)

Catalog # :

MA5-48148

Quantity :

200 ug

Price :

US 520.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: Assay-dependent, T-Cell Activation: Assay-dependent

Species :

Mouse

Clone :

LOB12.3

Isotype :

IgG2a, kappa

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.

Immunogen :

This antibody was generated by immunizing rats with recombinant CD137-Fc fusion protein.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent, T-Cell Activation: Assay-dependent

Aliases :

4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9