SIRP beta/gamma Recombinant Mouse Monoclonal Antibody (OX117) | Invitrogen MA5-47959 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SIRP beta/gamma Recombinant Mouse Monoclonal Antibody (OX117)

catalog :

MA5-47959

quantity :

200 ug

price :

US 520.00

clonality :

recombinant

host :

mouse

conjugate :

nonconjugated

clone name :

OX117

The same clone is also sold as:

Santa Cruz Biotechnology: sc-53112
Abcam: ab245690

reactivity :

human

application :

immunoprecipitation, flow cytometry

product information

Product Type :

Antibody

Product Name :

SIRP beta/gamma Recombinant Mouse Monoclonal Antibody (OX117)

Catalog # :

MA5-47959

Quantity :

200 ug

Price :

US 520.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Immunoprecipitation: Assay-dependent

Species :

Human

Clone :

OX117

Isotype :

IgG1, kappa

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

SIRP beta and SIRP gamma are two members of the signal regulatory protein (SIRP) family. These proteins are transmembrane receptors that are expressed on the surface of various cells, including immune cells and neurons. The function of SIRP beta and SIRP gamma is to regulate cellular signaling pathways that are involved in immune responses, cell adhesion, and phagocytosis. Specifically, these proteins interact with the protein tyrosine phosphatase SHP-1, which is a negative regulator of immune cell activation. By binding to SHP-1, SIRP beta and SIRP gamma can inhibit immune cell activation and promote immune tolerance. In addition to their role in immune regulation, SIRP beta and SIRP gamma have also been implicated in neuronal signaling and synaptic plasticity. These proteins are thought to play a role in the formation and maintenance of synapses, as well as in the regulation of neuronal activity.

Immunogen :

Recombinant human SIRPgamma:CD4 fusion protein.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Immunoprecipitation: Assay-dependent