Protein APC Monoclonal Antibody (KT44) | Invitrogen MA5-47696 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Protein APC Monoclonal Antibody (KT44)

catalog :

MA5-47696

quantity :

100 uL

price :

US 454.00

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

KT44

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

Protein APC Monoclonal Antibody (KT44)

Catalog # :

MA5-47696

Quantity :

100 uL

Price :

US 454.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Rat

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100, Western Blot: 1:1,000

Species :

Human, Mouse, Rat

Clone :

KT44

Isotype :

IgG2a

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

Immunogen :

Clone KT44 was generated from a recombinant protein containing amino acid residues from the central region mouse APC. This sequence is highly conserved in human and rat APC, and has low homology to APC2.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Western Blot: 1:1,000

Aliases :

adenomatosis polyposis coli; adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli; adenomatous polyposis coli protein; AI047805; APC; APC, WNT signaling pathway regulator; AU020952; AW124434; BTPS2; CC1; Deleted in polyposis 2.5; DP2; DP2.5; DP3; FAP; FPC; GS; mAPC; Min; multiple intestinal neoplasia; PPP1R46; Protein APC; protein phosphatase 1, regulatory subunit 46; RATAPC; truncated adenomatosis polyposis coli; WNT signaling pathway regulator