PIK3C2A Recombinant Rabbit Monoclonal Antibody (HL1612) | Invitrogen MA5-47109 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PIK3C2A Recombinant Rabbit Monoclonal Antibody (HL1612)

catalog :

MA5-47109

quantity :

100 uL

price :

US 444.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

HL1612

The same clone is also sold as:

Novus Biologicals: NBP3-25601

reactivity :

human, mouse, rat, dogs, cat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

PIK3C2A Recombinant Rabbit Monoclonal Antibody (HL1612)

Catalog # :

MA5-47109

Quantity :

100 uL

Price :

US 444.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Canine, Feline, Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:500-1:3,000

Species :

Canine, Feline, Human, Mouse, Rat

Clone :

HL1612

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The Class II PI3 kinases, including PIK3C2A, phosphorylate the 3 position of PI or PI4P. Though not as well studied as the Class I PI3 kinases, the Class II enyzmes have been linked to diverse, receptor-mediated cellular processes including insulin signaling, neuronal survival, and growth factor signaling. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.

Immunogen :

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human PI3 kinase C2 alpha. The exact sequence is proprietary.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:500-1:3,000

Aliases :

C2-containing phosphatidylinositol kinase; CPK; Cpk-m; DKFZp686L193; MGC142218; p170; phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha; phosphoinositide 3-kinase-C2-alpha; phosphoinositide-3-kinase, class 2, alpha polypeptide; PI3KC2; PI3-K-C2(ALPHA); pi3kc2a; PI3-K-C2A; PI3K-C2alpha; PI3K-C2-alpha; Pik3c2a; ptdIns-3-kinase C2 subunit alpha