GAD65 Recombinant Rabbit Monoclonal Antibody (HL1187) | Invitrogen MA5-46952 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GAD65 Recombinant Rabbit Monoclonal Antibody (HL1187)

catalog :

MA5-46952

quantity :

100 uL

price :

US 444.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

HL1187

reactivity :

human, mouse, rat, dogs, zebrafish , cat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

GAD65 Recombinant Rabbit Monoclonal Antibody (HL1187)

Catalog # :

MA5-46952

Quantity :

100 uL

Price :

US 444.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Canine, Feline, Human, Mouse, Rat, Zebrafish

Applications :

Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:500-1:3,000

Species :

Canine, Feline, Human, Mouse, Rat, Zebrafish

Clone :

HL1187

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

GAD65 (glutamic acid decarboxylase-65) are present in autoimmune disorders such as insulin-dependent (type1) diabetes mellitus (IDDM), stiff man syndrome and polyendocrine autoimmune disease. Auto-antibodies to GAD65 are present in 60-70% of individuals with newly diagnosed IDDM and thus are important markers for disease activity. These auto-antibodies usually recognize conformation-dependent regions on GAD65 and rarely bind to the second isoform, GAD67. Auto-antibodies to GAD67 are found in only 15% of recent-onset IDDM patients and most of this binding can be blocked with GAD65, suggesting shared epitopes between the two isoforms of GAD.

Immunogen :

Recombinant protein encompassing a sequence within the C-terminus region of human GAD65. The exact sequence is proprietary.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:500-1:3,000

Aliases :

6330404F12Rik; 65 kDa glutamic acid decarboxylase; GAD(65); GAD2; Gad-2; GAD65; GAD-65; Glutamate decarboxylase 2; Glutamate decarboxylase 2 (islet); glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); glutamate decarboxylase 65 kDa isoform; Glutamate decarboxylase-2 (pancreas); glutamic acid decarboxylase 2; glutamic acid decarboxylase 65; MGC161605; MGC161607; RP11-420F12.2