CD204 Recombinant Rabbit Monoclonal Antibody (004), PE | Invitrogen MA5-46792 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD204 Recombinant Rabbit Monoclonal Antibody (004), PE

catalog :

MA5-46792

quantity :

100 Tests

price :

US 420.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

clone name :

4

The same clone is also sold as:

Abcam: ab275707, ab277135, ab275706

reactivity :

mouse

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

CD204 Recombinant Rabbit Monoclonal Antibody (004), PE

Catalog # :

MA5-46792

Quantity :

100 Tests

Price :

US 420.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Mouse

Applications :

Flow Cytometry: 5 uL/test

Species :

Mouse

Clone :

Isotype :

IgG

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD204 gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. Diseases associated with MSR1 include Barrett Esophagus and Prostate Cancer.

Immunogen :

Recombinant protein encoding Mouse CD204 (Trp83-Val354).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL/test

Aliases :

bovine scavenger receptor type II; CD204; Macrophage acetylated LDL receptor I and II; macrophage scavenger receptor 1; macrophage scavenger receptor type III; macrophage scavenger receptor types I and II; MRS-A; MSR; Msr1; MSR-A; phSR1; phSR2; RGD1564316; SCARA1; Scavenger receptor class A member 1; scavenger receptor class A, member 1; scavenger receptor type A; scavenger receptor type I; Scvr; SRA; SR-A; SR-AI; SR-AI/II; SR-AII