CD150 Monoclonal Antibody (SLAM.4) | Invitrogen MA5-46198 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD150 Monoclonal Antibody (SLAM.4)

catalog :

MA5-46198

quantity :

100 ug

price :

US 359.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SLAM.4

The same clone is also sold as:

Bio-Rad: MCA6121PE
Exbio: A6-660-T100, 1A-660-T100, 10-660-C100, 1F-660-T025, 1P-660-T100, A4-660-T100, 10-660-C025, 1F-660-T100, 1P-660-T025
Abcam: ab176543
Santa Cruz Biotechnology: sc-101620
OriGene: AM26146AF-N

reactivity :

human

application :

immunocytochemistry, immunoprecipitation, flow cytometry

product information

Product Type :

Antibody

Product Name :

CD150 Monoclonal Antibody (SLAM.4)

Catalog # :

MA5-46198

Quantity :

100 ug

Price :

US 359.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1-3 ug/mL, Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent

Species :

Human

Clone :

SLAM.4

Isotype :

IgG1

Storage :

4 C, do not freeze

Description :

CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells. Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).

Immunogen :

Human CD150-transfected 300.19 cells

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1-3 ug/mL, Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent

Aliases :

4933415F16; AA177906; CD150; CD150 antigen; CDw150; ESTM51; IPO-3; RGD1560634; signaling lymphocyte activation molecule; signaling lymphocytic activation molecule; signaling lymphocytic activation molecule family member 1; Slam; SLAM family member 1; Slamf1