This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CaMKII alpha/beta Monoclonal Antibody (22B1), FITC
catalog :
MA5-45147
quantity :
100 ug
price :
US 410.00
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
22B1

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
CaMKII alpha/beta Monoclonal Antibody (22B1), FITC
Catalog # :
MA5-45147
Quantity :
100 ug
Price :
US 410.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse, Rat
Applications :
ELISA: Assay-dependent, Immunocytochemistry: 1:1,000, Immunohistochemistry (Paraffin): 1:100, Immunohistochemistry (PFA fixed): 1:5,000, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
Species :
Human, Mouse, Rat
Clone :
22B1
Isotype :
IgG1
Storage :
4 C, store in dark
Description :
Ca2+/Calmodulin-Dependent Protein Kinase II (CaM Kinase II) is a multi-functional calcium and calmodulin-dependent protein kinase that mediates cellular response to a wide variety of intercellular signals (Kennedy, 1998; Schulman and Hanson, 1993). CaM Kinase II has been shown to regulate diverse cellular functions including synaptic plasticity, neurotransmitter synthesis and release, gene expression, ion channel function, carbohydrate metabolism, cytoskeletal function, and Ca2+-homeostasis (Gleason et al., 2003; Soderling, 2000; Hudmon and Schulman, 2002). Phosphorylation of Thr286 on the kinase produces an autonomously active form of CaM Kinase II (Meng et al., 2003; Picciotto et al., 1993). Autophosphorylation of Thr305 inhibits the activity CaM Kinase II. Phosphorylation at this site appears to reduce the association of CaM Kinase II with the PSD and reduces LTP and learning (Elgersma et al., 2002).
Immunogen :
Synthetic peptide
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunocytochemistry: 1:1,000, Immunohistochemistry (Paraffin): 1:100, Immunohistochemistry (PFA fixed): 1:5,000, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
Aliases :
alpha CaM kinase II; alpha-CaMKII; Ca++/calmodulin-dependent protein kinase II beta subunit; Ca2+/calmodulin-dependent protein kinase II alpha; calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase II alpha; calcium/calmodulin-dependent protein kinase II alpha subunit; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase II, beta; calcium/calmodulin-dependent protein kinase type II alpha chain; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase type II subunit beta; caM kinase II subunit alpha; CaM kinase II subunit beta; CaMK II; Camk2a; Camk2b; Camk2d; CaMKII; caMK-II subunit alpha; caMK-II subunit beta; caM-kinase II alpha chain; caM-kinase II beta chain; Ck2b; mKIAA0968; PK2CDD; PKCCD; R74975
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA