STAT5 beta Recombinant Rabbit Monoclonal Antibody (BLR146J) | Invitrogen MA5-44480 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

STAT5 beta Recombinant Rabbit Monoclonal Antibody (BLR146J)

catalog :

MA5-44480

quantity :

10 uL

price :

US 147.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

BLR146J

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

STAT5 beta Recombinant Rabbit Monoclonal Antibody (BLR146J)

Catalog # :

MA5-44480

Quantity :

10 uL

Price :

US 147.00

Clonality :

Recombinant Monoclonal

Purity :

purified

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: 6 uL/1 mg lysate, Western Blot: 1:1,000

Species :

Human

Clone :

BLR146J

Isotype :

IgG

Storage :

4 C

Description :

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Immunogen :

Peptide representing a region between residue 737 and the C-terminus (residue 787) of Human Signal Transducer and Activator of Transcription 5B.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: 6 uL/1 mg lysate, Western Blot: 1:1,000

Aliases :

LOC101122961; mammary gland factor STAT5B; Signal transducer and activator of transcription 5a; signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; STAT5B; transcription factor STAT5B