CD38 Recombinant Rabbit Monoclonal Antibody (BLR123H) | Invitrogen MA5-44436 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD38 Recombinant Rabbit Monoclonal Antibody (BLR123H)

catalog :

MA5-44436

quantity :

10 uL

price :

US 147.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

BLR123H

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

CD38 Recombinant Rabbit Monoclonal Antibody (BLR123H)

Catalog # :

MA5-44436

Quantity :

10 uL

Price :

US 147.00

Clonality :

Recombinant Monoclonal

Purity :

purified

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: 20 uL/1 mg lysate, Western Blot: 1:1,000

Species :

Human

Clone :

BLR123H

Isotype :

IgG

Storage :

4 C

Description :

CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter's Syndrome.

Immunogen :

Recombinant protein representing the extracellular domain of Human ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (aka CD38, residues 43-300).

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: 20 uL/1 mg lysate, Western Blot: 1:1,000

Aliases :

2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADPRC1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; Cd38; CD38 antigen; CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase); CD38 antigen (p45); CD38 antigen p45; CD38 molecule; CD38H; Cd38-rs1; cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; I-19; NAD(+) nucleosidase; NAD+ nucleosidase; NIM-R5 antigen; T10