This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
T-bet Recombinant Rabbit Monoclonal Antibody (BLR110H)
catalog :
MA5-44411
quantity :
100 uL
price :
US 444.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
BLR110H

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
T-bet Recombinant Rabbit Monoclonal Antibody (BLR110H)
Catalog # :
MA5-44411
Quantity :
100 uL
Price :
US 444.00
Clonality :
Recombinant Monoclonal
Purity :
purified
Host :
Rabbit
Reactivity :
Human
Applications :
Flow Cytometry: 0.05 uL/1x10^6 cells, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: 6 uL/1 mg lysate, Western Blot: 1:1,000
Species :
Human
Clone :
BLR110H
Isotype :
IgG
Storage :
4 C
Description :
T-bet, also known as TBX21, is a T-cell specific transcription factor containing a single T-box DNA-binding domain. It controls the expression of the TH1 cytokine, interferon-gamma. Both Th1 and Th17 cells are crucial in immune regulation and autoimmune disease development. T-bet initiates Th1 lineage development from naive Th precursor cells and directs T cell differentiation to Th1 versus Th17. T-bet is cooperating with Stat4 (signal tranducer and activator of transcription 4) in programming chromatin architecture for Th1 gene expression. Genetic variations in T-bet are associated with susceptibility to aspirin-induced asthma and nasal polyps.
Immunogen :
Peptide representing a region between residue 485 and the C-terminus (residue 535) of Human T-box transcription factor TBX21.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.05 uL/1x10^6 cells, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: 6 uL/1 mg lysate, Western Blot: 1:1,000
Aliases :
HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA