This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Phospho-gamma-H2AX (Ser139) Recombinant Rabbit Monoclonal Antibody (BLR053F)
catalog :
MA5-44300
quantity :
10 uL
price :
US 147.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
BLR053F

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
Phospho-gamma-H2AX (Ser139) Recombinant Rabbit Monoclonal Antibody (BLR053F)
Catalog # :
MA5-44300
Quantity :
10 uL
Price :
US 147.00
Clonality :
Recombinant Monoclonal
Purity :
purified
Host :
Rabbit
Reactivity :
Human
Applications :
Flow Cytometry: 1 uL/1x10^6 cells, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: 20 uL/1 mg lysate, Western Blot: 1:1,000
Species :
Human
Clone :
BLR053F
Isotype :
IgG
Storage :
4 C
Description :
H2AX is a variant of the H2A protein family and is a component of the histone octomer in nucleosomes. H2AX is phosphorylated by kinases such as ataxia telangiectasia mutated (ATM) and ATM-Rad3-related (ATR) in the PI3K pathway. Gamma-H2AX is the first step in recruiting and localizing DNA repair proteins. DSBs can be induced by mechanisms such as ionizing radiation or cytotoxic agents and subsequently, gamma-H2AX foci quickly form. These foci represent the DSBs in a 1:1 manner and can be used as a biomarker for damage. The visualization of gamma-H2AX by can allow the assessment of DNA damage, related DNA damage proteins and DNA repair. Gamma-H2AX has applications in the detection of genomic damage caused by cytotoxic chemical agents and environmental and physical damage.
Immunogen :
Peptide surrounding phosphorylated serine 140 of human histone H2AX
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 uL/1x10^6 cells, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: 20 uL/1 mg lysate, Western Blot: 1:1,000
Aliases :
gamma H2A X; gamma H2A.X; gamma-H2A.X; gh2ax
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA