IDO1 Recombinant Rabbit Monoclonal Antibody (BLR040F) | Invitrogen MA5-44276 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IDO1 Recombinant Rabbit Monoclonal Antibody (BLR040F)

catalog :

MA5-44276

quantity :

20 uL

price :

US 147.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

BLR040F

The same clone is also sold as:

Abcam: ab243896

reactivity :

human

application :

western blot, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

IDO1 Recombinant Rabbit Monoclonal Antibody (BLR040F)

Catalog # :

MA5-44276

Quantity :

20 uL

Price :

US 147.00

Clonality :

Recombinant Monoclonal

Purity :

purified

Host :

Rabbit

Reactivity :

Human

Applications :

Immunoprecipitation: 15 uL/mg of lysate, Western Blot: 1:1,000

Species :

Human

Clone :

BLR040F

Isotype :

IgG

Storage :

4 C

Description :

IDO1 is an intracellular heme-containing enzyme that catalyzes the oxidative cleavage of the indole ring of several important regulatory molecules like tryptophan, serotonin, and melatonin. By doing this, IDO1 initiates the production of biologically active metabolites, commonly referred to as kynurenines. IDO1 is widely expressed in a variety of human tissues as well as in macrophages and dendritic cells (DCs). In inflammation, interferons (IFNs) act on specific receptors to trigger IDO1 induction. The production of IFN-gamma and induction of IDO1 represent important antimicrobial mechanisms. Degradation and depletion of tryptophan by IDO1 inhibits the growth of viruses, bacteria and parasites. Furthermore, IDO1 plays a complex and crucial role in immunoregulation during infection, pregnancy, autoimmunity, transplantation, and neoplasia.

Immunogen :

Recombinant protein representing human Indoleamine 2, 3-dioxygenase 1 (IDO1, residues 1-403).

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: 15 uL/mg of lysate, Western Blot: 1:1,000

Aliases :

EC 1.13.11.52; IDO; IDO1; IDO-1; INDO; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase