CDK7 Recombinant Rabbit Monoclonal Antibody (BL-80-5D4) | Invitrogen MA5-44208 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CDK7 Recombinant Rabbit Monoclonal Antibody (BL-80-5D4)

catalog :

MA5-44208

quantity :

20 uL

price :

US 147.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

BL-80-5D4

The same clone is also sold as:

Novus Biologicals: NBP2-76409

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

CDK7 Recombinant Rabbit Monoclonal Antibody (BL-80-5D4)

Catalog # :

MA5-44208

Quantity :

20 uL

Price :

US 147.00

Clonality :

Recombinant Monoclonal

Purity :

purified

Host :

Rabbit

Reactivity :

Human

Applications :

Flow Cytometry: 1 uL/1x10^6 cells, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: 20 uL/0.5 mg lysate, Western Blot: 1:1,000

Species :

Human

Clone :

BL-80-5D4

Isotype :

IgG

Storage :

4 C

Description :

The trimeric complex of CDK7, cyclin H and MNAT1, functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This complex is thought to serve as a direct link between the regulation of transcription and the cell cycle. The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). CDK7 may be a target of germline cancer-inducing mutations.

Immunogen :

Synthetic peptide representing a region between residues 300 and the C-terminus (residue 346) of human Cyclin-Dependent Kinase 7.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 uL/1x10^6 cells, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: 20 uL/0.5 mg lysate, Western Blot: 1:1,000

Aliases :

39 KDa protein kinase; 39 protein kinase; AI323415; AI528512; C230069N13; CAK; CAK1; CDK; CDK7; CDK-activating kinase; CDK-activating kinase 1; Cdkn7; cell division protein kinase 7; CR4 protein kinase; CRK4; CRK4 PK (CDC2-related-kinase-4 protein kinase); cyclin dependent kinase 7; cyclin-dependent kinase 7; cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog Xenopus laevis cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase); EC 2.7.11.22; EC 2.7.11.23; HCAK; homolog of Xenopus MO15 Cdk-activating kinase; kinase subunit of CAK; MO15; Mpk-7; OTTHUMP00000222032; OTTHUMP00000222033; p39 Mo15; p39MO15; Protein-tyrosine kinase MPK-7; serine/threonine kinase stk1; serine/threonine protein kinase 1; serine/threonine protein kinase MO15; Serine/threonine-protein kinase 1; STK1; TFIIH basal transcription factor complex kinase subunit