RPSA Monoclonal Antibody (RP-01), Alexa Fluor 488 | Invitrogen MA5-44138 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RPSA Monoclonal Antibody (RP-01), Alexa Fluor 488

catalog :

MA5-44138

quantity :

100 ug

price :

US 470.00

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

RP-01

The same clone is also sold as:

Novus Biologicals: NBP3-09109

reactivity :

human, mouse, chicken, bovine, Xenopus laevis

application :

western blot, immunocytochemistry, flow cytometry

product information

Product Type :

Antibody

Product Name :

RPSA Monoclonal Antibody (RP-01), Alexa Fluor 488

Catalog # :

MA5-44138

Quantity :

100 ug

Price :

US 470.00

Clonality :

Monoclonal

Purity :

Size-exclusion chromatography

Host :

Mouse

Reactivity :

Bovine, Chicken, Human, Mouse, Xenopus laevis

Applications :

Flow Cytometry: 4-10 ug/mL, Immunocytochemistry: Assay-dependent, Western Blot: Assay-dependent

Species :

Bovine, Chicken, Human, Mouse, Xenopus laevis

Clone :

RP-01

Isotype :

IgG2a

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Immunogen :

REPRLLVVTDPRADHQP

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 4-10 ug/mL, Immunocytochemistry: Assay-dependent, Western Blot: Assay-dependent

Aliases :

37 kDa laminin receptor; 37 kDa laminin receptor precursor; 37 kDa laminin receptor precursor {ECO:0000255; 37 kDa oncofetal antigen; 37/67 kDa laminin receptor; 37/67 kDa laminin receptor {ECO:0000255; 37LRP; 37LRP {ECO:0000255; 40S ribosomal protein SA; 40S ribosomal protein SA {ECO:0000255; 67 kDa laminin receptor; 67 kDa laminin receptor {ECO:0000255; 67kDa; 67LR; 67LR {ECO:0000255; AL022858; colon carcinoma laminin-binding protein; HAMAP-Rule:MF_03016}; ICAS; LAMBR; Laminin receptor 1; laminin receptor 1 (67kD, ribosomal protein SA); laminin receptor 1 (ribosomal protein SA); laminin receptor 1 {ECO:0000255; laminin-binding protein precursor p40; laminin-binding protein precursor p40 {ECO:0000255; LamR; lamR {ECO:0000255; LAMR1; Lamrl1; LBP; LBP/p40; LBP/p40 {ECO:0000255; LRP; LRP/LR; LRP/LR {ECO:0000255; MLR; Multidrug resistance-associated protein MGr1-Ag; NEM/1CHD4; OFA/iLRP; p40; P40-3; P40-3, functional; P40-8; P40-8, functional; ribosomal protein SA; Rpsa; rssa; SA; Small ribosomal subunit protein uS2