ADAMTS9 Monoclonal Antibody (D2) | Invitrogen MA5-43986 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ADAMTS9 Monoclonal Antibody (D2)

catalog :

MA5-43986

quantity :

100 uL

price :

US 444.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

reactivity :

human

application :

western blot

product information

Product Type :

Antibody

Product Name :

ADAMTS9 Monoclonal Antibody (D2)

Catalog # :

MA5-43986

Quantity :

100 uL

Price :

US 444.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human

Applications :

Western Blot: 0.01-2 ug/mL

Species :

Human

Clone :

Isotype :

IgG2b, kappa

Storage :

-20 C

Description :

ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The immunizing peptide sequence is 100% conserved between human, mouse and rat. ADAMTS9 is a member of the ADAMs family of proteinases with Thrombospondin motifs. ADAMTS9 is closest in homology to ADAMTS20, sharing 54% overall identity, and like ADAMTS20 ADAMTS9 gas a GON-like domain at the carboxyterminal end. The GON domain at the carboxyterminal end is similar to the GON-1 protein in C. elegans, mutations of which lead to defective gonadal development. ADAMTS9 is expressed in ovary and testis, but little is known about the role of ADAMTS9 in reproductive organs. ADAMTS9 is also expressed in the heart, placenta, lung, skeletal tissue, and pancreas, so the protein must have wider functions than just gonadal development. ADAMTS9, like ADAMTS20, has a total of 15 thrombospondin-like domains.

Immunogen :

Cys1727-Leu1935 (Accession Q9P2N4), with N-terminal His Tag

Format :

Liquid

Applications w/Dilutions :

Western Blot: 0.01-2 ug/mL

Aliases :

a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 9; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 9; ADAM metallopeptidase with thrombospondin type 1 motif, 9; ADAMs; ADAM-TS 9; ADAMTS9; JSCFDG; KIAA1312; metalloendopeptidases