HSPA1L Monoclonal Antibody (2-1#) | Invitrogen MA5-43764 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HSPA1L Monoclonal Antibody (2-1#)

catalog :

MA5-43764

quantity :

20 uL

price :

US 181.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2-1#

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

HSPA1L Monoclonal Antibody (2-1#)

Catalog # :

MA5-43764

Quantity :

20 uL

Price :

US 181.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 5-30 ug/mL, Immunohistochemistry (Paraffin): 5-30 ug/mL, Western Blot: 0.5-3 ug/mL

Species :

Human

Clone :

2-1#

Isotype :

IgG2b, kappa

Storage :

-20 C

Description :

In response to adverse changes in their environment, cells from many organisms increase the expression of a class of proteins referred to as heat shock proteins. One class of stress proteins, termed the 'small heat shock proteins' is comprised of a diverse group of proteins from approximately15 to >30 kDa, with a single form found in yeast and human cells and multiple related forms found in higher plants. A direct relationship between elevated strwess protein expression and neoplasia has been suggested from studies on estrogen-induced proteins in breast cancer cells. In addition, Hsp27 exhibits rapid increased phosphorylation in response to various mitogens, tumor promoter (e. g. phorbol esters) and calcium ionophores. The expression of a 24 kDa protein was shown to correlate with steroid hormone receptor in cell lines, organs, and tumors. The 24 kDa estrogen-induced protein was found to be expressed at high levels in carcinoma of the breast. Another study has suggested that levels of the Hsp27 correlate with endometrial adenocarcinomas. Interestingly, the regulation of human Hsp27 by estrogens and heat shock is reminiscent of the ecdysteroid and heat shock activation of the drosophila Hsp20 genes.

Immunogen :

Recombinant protein Heat Shock 70kDa Protein 1 Like Protein. The antigen corresponds to amino acid range 1-641 of the target protein.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5-30 ug/mL, Immunohistochemistry (Paraffin): 5-30 ug/mL, Western Blot: 0.5-3 ug/mL

Aliases :

heat shock 10kDa protein 1-like; heat shock 70 kDa protein 1-Hom; heat shock 70 kDa protein 1L; Heat shock 70 kDa protein 1-like; Heat shock 70 kDa protein 3; heat shock 70 kDa-like protein 1; heat shock 70kD protein-like 1; heat shock 70kDa protein 1-like; Heat shock protein; heat shock protein 1-like; Heat shock protein 70-1l; heat shock protein cognate 70, testis; heat shock protein family A (Hsp70) member 1 like; heat shock-related protein hsc70t; Hsc70t; HSP70.3; HSP70-1L; Hsp70-3; HSP70-HOM; HSP70T; Hspa1l; hum70t; inducible heat shock protein 70; Msh5; Spermatid-specific heat shock protein 70