This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Klotho Monoclonal Antibody (C3)
catalog :
MA5-43726
quantity :
100 uL
price :
US 444.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C3
reactivity :
human, rat
application :
western blot
product information
Product Type :
Antibody
Product Name :
Klotho Monoclonal Antibody (C3)
Catalog # :
MA5-43726
Quantity :
100 uL
Price :
US 444.00
Clonality :
Monoclonal
Purity :
Protein A/G
Host :
Mouse
Reactivity :
Human, Rat
Applications :
Western Blot: 0.01-2 ug/mL
Species :
Human, Rat
Clone :
C3
Isotype :
IgG1, kappa
Storage :
-20 C
Description :
KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling. KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor.
Immunogen :
Phe765-Ser981 (Accession Q9UEF7), with Two N-terminal Tags, His-tag and SUMO-tag
Format :
Liquid
Applications w/Dilutions :
Western Blot: 0.01-2 ug/mL
Aliases :
alpha-kl; HFTC3; Kl; Klotho; Klotho peptide; secreted form of Klotho protein
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA