TBX3 Recombinant Rabbit Monoclonal Antibody (3G9F1) | Invitrogen MA5-42931 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TBX3 Recombinant Rabbit Monoclonal Antibody (3G9F1)

catalog :

MA5-42931

quantity :

100 uL

price :

US 470.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

3G9F1

reactivity :

mouse, rat

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

TBX3 Recombinant Rabbit Monoclonal Antibody (3G9F1)

Catalog # :

MA5-42931

Quantity :

100 uL

Price :

US 470.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Mouse, Rat

Applications :

ELISA: 1 ug/mL, Western Blot: 1:100-1:500

Species :

Mouse, Rat

Clone :

3G9F1

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

T-box 3 (TBX3) is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. The Tbx3 protein is a transcriptional repressor that binds the canonical Brachychury bindig sites, and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Tbx3 is required for normal mammary development and is also implicated in tumor development. Tbx3 expression also increases during osteoblast differentiation, and may function as a determinant of osteoblast cell numbers. Mutations in T-box 3 cause ulnar-mammary syndrome (MIM 181450), affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing results in three transcript variants encoding different isoforms; however, the nature of one full length variant has not been determined. Subsets of human breast cancer cell lines overexpress TBX36. in vitro, Tbx3 overexpression in mouse embryo fibroblasts leads to immortalization of cells. Truncated forms of Tbx3 are increased in plasma samples.

Immunogen :

A synthetic peptide corresponding to a sequence within amino acids 644-743 of human Tbx3 (O15119).

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Western Blot: 1:100-1:500

Aliases :

bladder cancer related protein XHL; D5Ertd189e; T-box 3; T-box 3 (ulnar mammary syndrome); T-box protein 3; T-box transcription factor TBX3; TBX3; TBX3-ISO; UMS; XHL