This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
HIRA Recombinant Rabbit Monoclonal Antibody (6Q7Y6)
catalog :
MA5-42899
quantity :
100 uL
price :
US 470.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
6Q7Y6
reactivity :
human
application :
western blot, ELISA
product information
Product Type :
Antibody
Product Name :
HIRA Recombinant Rabbit Monoclonal Antibody (6Q7Y6)
Catalog # :
MA5-42899
Quantity :
100 uL
Price :
US 470.00
Clonality :
Recombinant Monoclonal
Purity :
Affinity Chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
ELISA: 1 ug/mL, Western Blot: 1:500-1:1,000
Species :
Human
Clone :
6Q7Y6
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochromatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
Immunogen :
Recombinant fusion protein containing a sequence corresponding to amino acids 550-675 of human HIRA (P54198).
Format :
Liquid
Applications w/Dilutions :
ELISA: 1 ug/mL, Western Blot: 1:500-1:1,000
Aliases :
AA138857; D16Ertd95e; DGCR1; DiGeorge critical region gene 1; Gm15797; HIR; HIR histone cell cycle regulation defective homolog A; Hira; histone cell cycle regulation defective homolog A; histone cell cycle regulation defective homolog A (S. cerevisiae); histone cell cycle regulator; N28177; OTTMUSG00000026264; Protein HIRA; TUP1; TUP1-like enhancer of split gene 1; TUP1-like enhancer of split protein 1; TUPLE1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
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