This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PR3 Recombinant Rabbit Monoclonal Antibody (3I3M1)
catalog :
MA5-42734
quantity :
100 uL
price :
US 470.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
3I3M1
reactivity :
human, mouse
application :
immunocytochemistry
product information
Product Type :
Antibody
Product Name :
PR3 Recombinant Rabbit Monoclonal Antibody (3I3M1)
Catalog # :
MA5-42734
Quantity :
100 uL
Price :
US 470.00
Clonality :
Recombinant Monoclonal
Purity :
Affinity Chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200
Species :
Human, Mouse
Clone :
3I3M1
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). [UniProt]
Immunogen :
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Proteinase 3/PR3 (P24158).
Format :
Liquid
Applications w/Dilutions :
ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200
Aliases :
ACPA; AGP7; azurophil granule protein 7; CANCA; C-ANCA; C-ANCA antigen; leukocyte proteinase 3; MBN; MBT; mPR3; Myeloblastin; neutrophil proteinase 4; NP4; NP-4; P29; PR3; PR-3; Proteinase 3; PRTN3; serine proteinase, neutrophil; wegener autoantigen; Wegener granulomatosis autoantigen
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA