CD80 Monoclonal Antibody (MEM-233), Alexa Fluor 700 | Invitrogen MA5-38747 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD80 Monoclonal Antibody (MEM-233), Alexa Fluor 700

catalog :

MA5-38747

quantity :

100 Tests

price :

US 418.00

clonality :

monoclonal

host :

mouse

conjugate :

AF700

clone name :

MEM-233

The same clone is also sold as:

OriGene: SM1742RP, SM1742P, SM1742PP, SM1742AC, SM1742A, SM1742F, SM1742PS
Abcam: ab27554, ab18279, ab82410, ab8239
Exbio: T8-287-T100, PB-287-T100, 1A-287-T025, 1P-287-T100, A7-287-T025, 11-287-C025, 1P-287-T025, A7-287-T100, PB-287-T025, 11-287-C100, T7-287-T100, PC-287-T100, T8-287-T025, 1A-287-T100, 1F-287-T025, PC-287-T025, 1F-287-T100, T7-287-T025
Bio-Rad: MCA2071A647, MCA2071GA

reactivity :

human

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

CD80 Monoclonal Antibody (MEM-233), Alexa Fluor 700

Catalog # :

MA5-38747

Quantity :

100 Tests

Price :

US 418.00

Clonality :

Monoclonal

Purity :

Size-exclusion chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 4 uL/1x10^6 cells

Species :

Human

Clone :

MEM-233

Isotype :

IgG1

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

Immunogen :

Extracellular domain of human CD80 fused to human IgG1(Fc)

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 4 uL/1x10^6 cells

Aliases :

Activation B7-1 antigen; B7; B7 protein; B7.1; B71; B7-1; B7-1 protein; B7-1 protein precursor; BB1; B-lymphocyte activation antigen B7; Cd28l; CD28LG; CD28LG1; CD80; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); CD80 anitgen; CD80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); Cd80 molecule; CD80 protein precursor; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; Ly53; Ly-53; MIC17; sCD 80; sCD80; secreted B7-1 protein precursor; soluble CD 80; soluble CD80; T-cell costimulatory molecule; T-cell co-stimulatory protein B7-1; T-lymphocyte activation antigen CD80; TS/A-1; TSA1