Langerin Monoclonal Antibody (2E1B2) | Invitrogen MA5-38473 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Langerin Monoclonal Antibody (2E1B2)

catalog :

MA5-38473

quantity :

100 ug

price :

US 484.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2E1B2

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
x15a mieszek A, Marcinkowska K, Ma x142 as Z, Sikora M, K x119 pska M, Nowakowska B, et al. Identification and characterization of stromal-like cells with CD207+/low CD1a+/low phenotype derived from histiocytic lesions - a perspective in vitro model for drug testing. BMC Cancer. 2024;24:105 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Langerin Monoclonal Antibody (2E1B2)

Catalog # :

MA5-38473

Quantity :

100 ug

Price :

US 484.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000

Species :

Human

Clone :

2E1B2

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.

Immunogen :

Purified recombinant fragment of human CD207 (aa: 65-328) expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000

Aliases :

CD 207 antigen; CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CD207 molecule, langerin; CLEC4K; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; Langerhans cell specific c-type lectin; langerin; RGD1565913