This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MEKK3 Recombinant Rabbit Monoclonal Antibody (ARC2074)
catalog :
MA5-38090
quantity :
100 uL
price :
US 484.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
ARC2074
reactivity :
human, mouse
application :
western blot, ELISA
product information
Product Type :
Antibody
Product Name :
MEKK3 Recombinant Rabbit Monoclonal Antibody (ARC2074)
Catalog # :
MA5-38090
Quantity :
100 uL
Price :
US 484.00
Clonality :
Recombinant Monoclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
ELISA: 1 ug/mL, Western Blot: 1:500-1:2,000
Species :
Human, Mouse
Clone :
ARC2074
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
MAP3K3 (MEKK3) directly regulates MAPK8 and extracellular signal-regulated protein kinase (ERK) pathways by phosphorylating multiple MAP2Ks. Northern blot analysis revealed a 4. 6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively; it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Immunogen :
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MEKK3 (Q99759)
Format :
Liquid
Applications w/Dilutions :
ELISA: 1 ug/mL, Western Blot: 1:500-1:2,000
Aliases :
AW548911; MAP/ERK kinase kinase 3; MAP3K3; MAPK/ERK kinase kinase 3; MAPKKK3; MEK kinase 3; MEKK 3; Mekk3; mitogen activated protein kinase kinase kinase 3; mitogen-activated protein kinase kinase kinase 3; mKIAA4031
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA